For the past 6 months, I’ve been spending a lot of time of time applying object oriented architecture principles to a rather large ColdFusion application. We are employing Transfer for our ORM, ColdSpring as our dependency injection engine, and Fusebox 5.1 as our web UI framework. This initial architecture was already in Fusebox 4, so we stayed it rather than moving to Model-Glue or Mach-II (the more innately OO CF frameworks).
Be on the lookout for a bunch a new posts around these topics.